 No shots. No drugs. Just science that works. |
 A capsule. Not an injection. Clinically proven weight loss. |
 FDA-cleared. Drug-free. Proven in the clinic. |
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Doctor-prescribed in 50 states
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FDA-cleared prescription for adults with a BMI of 25 and up. No qualifying condition required to start. |
 Drug-free, needle-free, non-surgical approach to weight management. |
 100% online physician visit, no insurance required. Available in all 50 states. |
100% Online
Doctor-prescribed in 50 states
No insurance required
Early weight loss with Epitomee® treatment (losing at least 2% at week 8) resulted in an average weight loss of 9.3% within 24 Weeks²
*Results reflect an average; individual results may vary.
I’m especially excited about Epitomee as an option for patients who struggle with hunger control at specific times of the day-particularly in the evening, which is a common challenge. Many individuals report good appetite control during the day but experience a resurgence of cravings or loss of dietary control in the late afternoon or evening. In these cases, Epitomee may offer satiety support during these high-risk periods, helping patients better adhere to their nutritional plans.
Epitomee offers a flexible, safe, and well-tolerated weight management solution suitable for a wide range of patients across different stages of their weight loss journey. It is an outstanding addition to the army of medications and medical devices that we have today.
I see the Epitomee capsule as an important tool in my toolbox due to its promising weight management treatment. Individuals who struggle with portion control or early satiety and have had little success with diet and exercise are good candidates for Epitomee treatment.
Epitomee supports clinically meaningful weight loss and fits seamlessly into a structured lifestyle approach. When combined with the right behavioral tools, it can help people lose weight and maintain their progress for the long term.
The idea of a capsule that simulates food and causes a feeling of satiety is coming to market. There is a large group of patients who can benefit from this device, which is effective and safe without significant side effects.
Epitomee capsule is a safe and effective, non-pharmacological option for weight management with broad application in patients with overweight or obesity. Because the Epitomee treatment was found to be safe, without any difference between placebo and epitome groups in overall and in gastrointestinal-related AEs. and well-tolerated, it can be used for a wide variety of patients, even those who might not tolerate other medications or have contraindications for those medications.
Epitomee is a good addition to our treatment toolbox – the safety, tolerability and efficacy profile make it a good fit for many patient types and for both weight loss and to aid in weight loss maintenance. We see a significant advantage in using Epitomee for individuals starting at a BMI of 25, a category where most anti-obesity medications are still not approved, regardless of whether additional health complications are present.
The Epitomee capsule offers a promising non-pharmacological option for overweight people especially for those patients with metabolic syndrome, where managing weight and improving cardiometabolic parameters is essential. Its favorable safety and tolerability profile makes it a practical addition to our treatment approach, with potential benefits in weight reduction, glycemic control, and overall cardiometabolic risk management.
Each Epitomee® Capsule contains a proprietary polymer blend that gently expands in the stomach after being taken with water, forming a soft, gel-like structure. This structure creates a natural* feeling of fullness, signaling the brain to help you feel satiety—so you can eat smaller portions without feeling deprived.
The Mechanism of Action
Drug-Free Technology That Works
The Epitomee® Capsule represents a new frontier in weight management—combining advanced material science with a simple, natural mechanism of action. Each Capsule contains a proprietary polymer blend that gently expands in the stomach after being taken with water, forming a semi-rigid, gel-like triangle structure. Here’s how it works.
Who it’s for
Use our BMI chart to see if you could benefit from taking the Epitomee® Capsule to reach your weight management goals.
Epitomee is a prescription medical device and should be taken under the guidance and supervision of a healthcare provider.
 Indicated for individuals with overweight or obesity who are 18+ years old, with a BMI of 25 kg/m2-40 kg/m2. The Epitomee® capsule may be considered for adults with or without comorbidities, subject to the judgment of a healthcare provider and in accordance with the instructions for use. |
 For individuals who want a non-drug, non-surgical approach. |
 For individuals who are not eligible for other weight management options, subject to the judgment of a healthcare provider. |
 For individuals who struggle with portion control or early satiety and have had little success with diet and exercise. |
What You Can Expect
The Epitomee® Capsule mechanism of action helps you feel full sooner and stay satisfied longer, so you can eat less without feeling deprived. Supporting appetite control makes it easier to reduce cravings and stick to your weight loss goals.
The Epitomee® Capsule is designed to fit seamlessly into your daily routine. Just take one capsule with water before your two main meals—no complicated schedules, no drastic lifestyle changes. It works in the background, helping you stay on track.
With Epitomee®, there’s no need for crash diets or restrictive meal plans. It supports natural portion control, so you can enjoy the foods you love—just in smaller amounts. It’s a manageable approach to weight loss that works with your body, not against it.
Epitomee® offers a non-pharmaceutical approach to weight management. Clinical studies show it’s well-tolerated, with no stimulants, no systemic absorption, and none of the harsh side effects often seen with weight loss drugs.
Extended use with Epitomee® was shown to be associated with weight loss maintenance as tested in a 48 weeks ELECT study.1
How it works
Frequently Asked Questions
Please refer to the Instructions for Use (IFU) for complete information. The response below does not include all relevant details.
The Epitomee® capsule is intended to facilitate weight loss in patients aged 18 and older who are overweight (BMI 25-30 kg/m2) or obese (BMI 30-40 kg/m2) who have not achieved desired results through diet and exercise. The Epitomee® capsule is intended to be used as an adjunct to diet and exercise. It can be suitable for individuals with or without comorbidities, including those who are ineligible for or do not want other weight loss medications, such as injections, under the supervision of a healthcare provider. Donna H. Ryan MD, Professor Emerita at Pennington Biomedical Research Center, mentioned that Epitomee® is a good fit for many patient types, and that it offers a significant advantage for individuals at a BMI of 25 to 30 who have no co-morbidities, a category where most anti-obesity medications are still not approved. Professor Jamy Ard also stated that Epitomee® is a safe and effective, non-pharmacological option for weight management, with broad application in patients who are overweight or obese. It can be used for a wide variety of patients, including those who may not tolerate other medications or have contraindications to them.
You must not use Epitomee® in the following situations:
Check with your health care providers if you can use Epitomee® if you have the following medical history:
Epitomee® is a swallowable capsule that helps you manage your weight. It is classified as a medical device, not a drug. Once swallowed with water, the capsule disintegrates in the stomach and releases a device that absorbs water and expand to form a three-dimensional triangular structure. This structure occupies volume in the stomach, creating a sensation of fullness earlier and helping you eat less throughout the day. The device works mechanically only and is drug-free.
Please refer to the Instructions for Use (IFU) for complete information. The response below does not include all relevant details.
If you missed a pre-meal dose, take Epitomee® during that meal, making sure to follow the directions for use and swallow one capsule with two glasses of water.
I always try diets and fail very quickly, now I am holding up because of the capsule.
Study participant
Surprisingly, I was very satiated after dinner and couldn’t finish my normal meal.
Study participant
It helps a lot with eating less and avoiding snacking between meals.
Study participant
I have no urge to snack during the afternoon and have a light meal in the evening.
Study participant
I’m less hungry during the day and between meals.
Study participant
Where your care comes from
Every part of your care happens domestically, under US oversight.
How we compare
A proven system that removes the guesswork and delivers real results.
Epitomee® treatments
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